Amit Sheth

Amit Kumar Pandey

Amit Sinhal

Abhinav Shrivastava

This book contains the latest computational intelligence methodologies and applications. This book is a collection of selected papers presented at International Conference on Sustainable Computing and Intelligent Systems (SCIS 2021), held in Jaipur, India, during February 5–6, 2021. It includes novel and innovative work from experts, practitioners, scientists, and decision-makers from academia and industry. It covers selected papers in the area of artificial intelligence and intelligent systems, intelligent business systems, machine intelligence, computer vision, Web intelligence, big data analytics, swarm intelligence, and related topics.

Proceedings of SCIS 2021

Intelligent Systems

Gautam Sethi

Manoj Garg

Transcription and Translation in Health and Disease provides a detailed overview of the regulators underlying transcription and translation in relation to a variety of human diseases and disorders. Beginning with an introduction into the current perspectives relating to these processes in human disease, the book expands to focus on specific mechanisms underlying conditions such as arthritis, cancer, neurological disorders, diabetes and cardiovascular disease. This book considers RNA processing and related mechanisms in eukaryotes including RNA splicing, RNA binding proteins, RNA interference, microRNAs, RNA editing, transcription factors, RNAi screening, CRISPR activation, CRISPR-Cas9 interference, and post-translational modifications. It provides a structured and detailed overview of the various regulators underlying molecular processes and their impact on health and disease, equipping readers with the necessary knowledge for further investigation in the areas of treatment and therapeutic intervention. Discusses the role played by transcription and translational regulation in various diseases, including cancer, diabetes, cardiovascular disease and neurological disease Considers a range of post-transcriptional regulators, including RNA-binding proteins, non-coding RNAs, epigenetic modifiers, alternative splicing and telomerase-binding proteins Covers the topic from fundamental knowledge to the latest developments in clinical application Includes a section dedicated to therapeutic applications

Amit Kumar Pandey

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