Andrew B. Lawson

Maria Dolores Ugarte

Sudipto Banerjee

Robert P. Haining

Handbook of Spatial Epidemiology explains how to model epidemiological problems and improve inference about disease etiology from a geographical perspective. Top epidemiologists, geographers, and statisticians share interdisciplinary viewpoints on analyzing spatial data and space–time variations in disease incidences. These analyses can provide important information that leads to better decision making in public health. The first part of the book addresses general issues related to epidemiology, GIS, environmental studies, clustering, and ecological analysis. The second part presents basic statistical methods used in spatial epidemiology, including fundamental likelihood principles, Bayesian methods, and testing and nonparametric approaches. With a focus on special methods, the third part describes geostatistical models, splines, quantile regression, focused clustering, mixtures, multivariate methods, and much more. The final part examines special problems and application areas, such as residential history analysis, segregation, health services research, health surveys, infectious disease, veterinary topics, and health surveillance and clustering. Spatial epidemiology, also known as disease mapping, studies the geographical or spatial distribution of health outcomes. This handbook offers a wide-ranging overview of state-of-the-art approaches to determine the relationships between health and various risk factors, empowering researchers and policy makers to tackle public health problems.

Handbook of Spatial Epidemiology

Focusing on data commonly found in public health databases and clinical settings, Bayesian Disease Mapping: Hierarchical Modeling in Spatial Epidemiology provides an overview of the main areas of Bayesian hierarchical modeling and its application to the geographical analysis of disease. The book explores a range of topics in Bayesian inference and

Hierarchical Modeling in Spatial Epidemiology

Bayesian Disease Mapping

Ken Kleinman

Following the events of 9/11 and in the current world climate, there is increasing concern of the impact of potential bioterrorism attacks. Spatial surveillance systems are used to detect changes in public health data, and alert us to possible outbreaks of disease, either from natural resources or from bioterrorism attacks. Statistical methods play a key role in spatial surveillance, as they are used to identify changes in data, and build models of that data in order to make predictions about future activity. This book is the first to provide an overview of all the current key methods in spatial surveillance, and present them in an accessible form, suitable for the public health professional. It features an abundance of examples using real data, highlighting the practical application of the methodology. It is edited and authored by leading researchers and practitioners in spatial surveillance methods. Provides an overview of the current key methods in spatial surveillance of public health data. Includes coverage of both single and multiple disease surveillance. Covers all of the key topics, including syndromic surveillance, spatial cluster detection, and Bayesian data mining.

Spatial and Syndromic Surveillance for Public Health

Emmanuel Lesaffre

The growth of biostatistics has been phenomenal in recent years and has been marked by considerable technical innovation in both methodology and computational practicality. One area that has experienced significant growth is Bayesian methods. The growing use of Bayesian methodology has taken place partly due to an increasing number of practitioners valuing the Bayesian paradigm as matching that of scientific discovery. In addition, computational advances have allowed for more complex models to be fitted routinely to realistic data sets. Through examples, exercises and a combination of introductory and more advanced chapters, this book provides an invaluable understanding of the complex world of biomedical statistics illustrated via a diverse range of applications taken from epidemiology, exploratory clinical studies, health promotion studies, image analysis and clinical trials. Key Features: Provides an authoritative account of Bayesian methodology, from its most basic elements to its practical implementation, with an emphasis on healthcare techniques. Contains introductory explanations of Bayesian principles common to all areas of application. Presents clear and concise examples in biostatistics applications such as clinical trials, longitudinal studies, bioassay, survival, image analysis and bioinformatics. Illustrated throughout with examples using software including WinBUGS, OpenBUGS, SAS and various dedicated R programs. Highlights the differences between the Bayesian and classical approaches. Supported by an accompanying website hosting free software and case study guides. Bayesian Biostatistics introduces the reader smoothly into the Bayesian statistical methods with chapters that gradually increase in level of complexity. Master students in biostatistics, applied statisticians and all researchers with a good background in classical statistics who have interest in Bayesian methods will find this book useful.

Bayesian Biostatistics

This book provides an authoritative account of Bayesian methodology, from its most basic elements to its practical implementations, with an emphasis on healthcare techniques. Contains introductory explanations of Bayesian principles common to all areas.

Andrew B. Lawson

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