Yang Wang

Yu-Hang Zhang

Anwen Shao

Xiang Xue

Dongmei Zhang 

The class of highly bioactive chemicals known as reactive oxygen species (ROS) has been extensively explored in relation to several malignancies and is thought to be a typical by-product of many cellular functions. Cancer cells have greater baseline ROS concentrations than healthy cells because of an imbalance between oxidants and antioxidants. At low to moderate levels, ROS functions as a signal transducer to drive cell proliferation, migration, invasion, and angiogenesis. ROS also has a second role in cellular metabolism. On the other hand, excessive ROS may kill cells by harming organelles, membranes, lipids, proteins, and nucleic acids. Numerous studies have shown that anticancer treatments that regulate ROS levels, such as immunotherapy, provide encouraging outcomes both in vitro and in vivo.

Reactive Oxygen Species (ROS): Key Components in Cancer Immunotherapy

Dirk M. Hermann

Lei Huang

Gaiqing Wang

Qifu Li

Yue He

Brain Injury and Repair Following Cerebrovascular Diseases: From Bench to Bedside

Anwen Shao

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