Charles O. Thoen

Asseged B. Dibaba

Nicolaas P. J. Kriek

This book recounts the biology of M. bovis, followed by the status of bovine Tuberculosis (bTB) in African countries, primarily based on zoonotic and epidemiological field reports. Since the accumulation of data is valueless unless it led to practicable control measures, emphasis is put on locally adapted protocols for future control of the disease. In order to systematically evaluate the knowledge base of bTB, Epidemiologic Problem Oriented Approach (EPOA) methodology was used. The methodology is composed of two triads: i) the problem identification/characterization triad, which is mainly descriptive in nature, and ii) the problem management/solution/mitigation triad, which is mainly geared toward problem management/solution (see figure). The first triad comprises three pillars: i) agent ii) host, and iii) environment and the second one: i) therapeutics/treatment, ii) prevention/control, and iii) health maintenance/promotion. The two triads are linked together by the diagnostic procedure linkage. The systematic and detailed studies of the ‘Host-Agent-Environment’ interactions are the building blocks to the understanding of agent transmission pathways and disease spread. These may include data about the disease status of the country, the nature of the disease agent and its hosts, the modes of transmission, the wildlife reservoirs in nature, persistence of infection, and agent survival in animal products and the environment. The problem identification and characterization triad identifies these interactions. Once a problem has been identified and well understood, the next step is to minimize the risk of transmission and spread of a disease. This area, referred to as problem solution/management triad, consists of problem management alternatives that rely upon prevention/control, and health maintenance/promotion of the disease in livestock, wildlife, and humans with the emphasis on resource-poor, developing countries in Africa.

Tuberculosis in Animals: An African Perspective

John F. Prescott

Carlton L. Gyles

J. Glenn Songer

Pathogenesis of Bacterial Infections in Animals, Fourth Edition captures the rapid developments in understanding the mechanisms of virulence of the major bacterial pathogens of animals. Now including a color plate section, the book presents an overview of pathogenesis, including relevant events that occur in the herd or flock and its environment, and activities that take place at the cellular and molecular levels. With contributions from 64 experts in the field, this book serves as a great reference for graduate students in veterinary medicine and animal science, microbiologists, virologists and pathologists.

Pathogenesis of Bacterial Infections in Animals

James H. Steele

Michael J. Gilsdorf

Mycobacterium bovis Infection in Animals and Humans

This much-anticipated third edition again consolidates the knowledge of more than twenty experts on pathogenesis of animal disease caused by various species or groups of bacteria. Emphasizing pathogenic events at the molecular and cellular levels, the editors and contributors place these developments in the context of the overall picture of disease. Pathogenesis of Bacterial Infections in Animals, Third edition, updates and expands the content of the second edition and includes cutting-edge information from the most current research. Comments on previous editions: "...highly recommended." --The Veterinary Record "...a comprehensive, complete and easy-to-use source of information." --Veterinary Microbiology "...recommended for graduate students and specialists in microbiology, pathology and infectious disease." --U.S. Animal Health Association Newsletter "...a wonderful book." --Journal of the American Veterinary Medical Association "...highly recommended." --The Cornell Veterinarian Graduate students, faculty, researchers, and specialists in microbiology, pathology, and infectious diseases will benefit from this highly-detailed and expanded edition of a popular and well-read veterinary text.

John B. Kaneene

Zoonotic Tuberculosis: Mycobacterium bovis and OtherPathogenic Mycobacteria, Third Edition is a comprehensivereview of the state of the art in the control and elimination ofinfections caused by Mycobacterium tuberculosis complex inanimals and humans. This update to the most complete and currentreference available on Mycobacterium bovis includes newcoverage of the latest molecular techniques; more information onhuman infection and One Health; updates to the information on theInternational Union Against Tuberculosis and Lung Disease (IUATLD),the World Health Organization (WHO), Pan American HealthOrganization (PAHO), and the United States Department ofAgriculture’s (USDA) National Tuberculosis EradicationProgram; and coverage of additional African countries. TheThird Edition upholds the book’s reputation as a truly globalresource on M. bovis. Written by an international list of tuberculosis experts,chapters cover the status of tuberculosis in many regionsthroughout the world and deal with issues related to the detection,spread, and control of Mycobacterium bovis, as well as theeconomic impact of outbreaks. Zoonotic Tuberculosis:Mycobacterium bovis and Other Pathogenic Mycobacteria offersvaluable information for public health officials, medical doctors,state and federal regulatory veterinarians, veterinarypractitioners, and animal caretakers.

Charles O. Thoen

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