Chengqi Zhang

Qingfeng Chen

Baoshan Chen

This book is organized into thirteen chapters that range over the relevant approaches and tools in data integration, modeling, analysis and knowledge discovery for signaling pathways. Having in mind that the book is also addressed for students, the contributors present the main results and techniques in an easily accessed and understood way together with many references and instances. Chapter 1 presents an introduction to signaling pathway, including motivations, background knowledge and relevant data mining techniques for pathway data analysis. Chapter 2 presents a variety of data sources and data analysis with respect to signaling pathway, including data integration and relevant data mining applications. Chapter 3 presents a framework to measure the inconsistency between heterogenous biological databases. A GO-based (genome ontology) strategy is proposed to associate different data sources. Chapter 4 presents identification of positive regulation of kinase pathways in terms of association rule mining. The results derived from this project could be used when predicting essential relationships and enable a comprehensive understanding of kinase pathway interaction. Chapter 5 presents graphical model-based methods to identify regulatory network of protein kinases. A framework using negative association rule mining is introduced in Chapter 6 to discover featured inhibitory regulation patterns and the relationships between involved regulation factors. It is necessary to not only detect the objects that exhibit a positive regulatory role in a kinase pathway but also to discover those objects that inhibit the regulation. Chapter 7 presents methods to model ncRNA secondary structure data in terms of stems, loops and marked labels, and illustrates how to find matched structure patterns for a given query. Chapter 8 shows an interval-based distance metric for computing the distance between conserved RNA secondary structures. Chapter 9 presents a framework to explore structural and functional patterns of RNA pseudoknot structure according to probability matrix. Chapter 10 presents methods to model miRNA data and identify miRNA interaction of cross-species and within-species. Chapter 11 presents an approach to measure the importance of miRNA site and the adjacent base by using information redundancy and develops a novel measure to identify strongly correlated infrequent itemsets. The discover association rules not only present important structural features in miRNAs, but also promote a comprehensive understanding of regulatory roles of miRNAs. Chapter 12 presents bioinformatics techniques for protein kinase data management and analysis, kinase pathways and drug targets, and describes their potential application in pharmaceutical industry. Chapter 13 presents a summary of the chapters and give a brief discussion to some emerging issues.

Model and Pattern Identification

Intelligent Strategies for Pathway Mining

Pacific Rim International Conference on Artificial Intelligence

This book constitutes the refereed proceedings of the 8th Pacific Rim International Conference on Artificial Intelligence, PRICAI 2004, held in Auckland, New Zealand in August 2004. The 94 revised full papers and 45 revised poster papers presented together with 3 invited contributions were carefully reviewed and selected from 356 submissions. The papers are organized in topical sections on logic and reasoning, knowledge representation and search, ontologies, planning, constraint satisfaction, machine learning, computational learning, Bayesian networks, evolutionary computing, neural networks, fuzzy logic, data mining, classification and clustering, case-based reasoning, information retrieval, agent technology, robotics, bioinformatics, image processing and computer vision, natural language processing, and speech understanding and interaction.

8th Pacific Rim International Conference on Artificial Intelligence, Auckland, New Zealand, August 9-13, 2004, Proceedings

PRICAI 2004: Trends in Artificial Intelligence

Philip S. Yu

Jing He

Peng Zhang

Wei Huang

Yong Shi

Yingjie Tian

Yangyong Zhu

This book constitutes the refereed proceedings of the Second International Conference on Data Science, ICDS 2015, held in Sydney, Australia, in August 8-9, 2015. The 19 revised full papers and 5 short papers presented were carefully reviewed and selected from 31 submissions. The papers focus on the following topics: mathematical issues in data science; big data issues and applications; data quality and data preparation; data-driven scientific research; evaluation and measurement in data service; big data mining and knowledge management; case study of data science; social impacts of data science.

Second International Conference, ICDS 2015, Sydney, Australia, August 8-9, 2015, Proceedings

Data Science

Shichao Zhang

The present volume arose from the need for a comprehensive coverage of the state of the art in security protocol analysis. It aims to serve as an overall course-aid and to provide self-study material for researchers and students in formal methods theory and applications in e-commerce, data analysis and data mining. The volume will also be useful to anyone interested in secure e-commerce. The book is organized in eight chapters covering the main approaches and tools in formal methods for security protocol analysis. It starts with an introductory chapter presenting the fundamentals and background knowledge with respect to formal methods and security protocol analysis. Chapter 2 provides an overview of related work in this area, including basic concepts and terminology. Chapters 3 and 4 show a logical framework and a model checker for analyzing secure transaction protocols. Chapter 5 explains how to deal with uncertainty issues in secure messages, including inconsistent messages and conflicting beliefs in messages. Chapter 6 integrates data mining with security protocol analysis, and Chapter 7 develops a new technique for detecting collusion attack in security protocols. Chapter 8 gives a summary of the chapters and presents a brief discussion of some emerging issues in the field.

Models and Applications

Secure Transaction Protocol Analysis

Zili Zhang (Ph.D.)

Solving complex problems in real-world contexts, such as financial investment planning or mining large data collections, involves many different sub-tasks, each of which requires different techniques. To deal with such problems, a great diversity of intelligent techniques are available, including traditional techniques like expert systems approaches and soft computing techniques like fuzzy logic, neural networks, or genetic algorithms. These techniques are complementary approaches to intelligent information processing rather than competing ones, and thus better results in problem solving are achieved when these techniques are combined in hybrid intelligent systems. Multi-Agent Systems are ideally suited to model the manifold interactions among the many different components of hybrid intelligent systems. This book introduces agent-based hybrid intelligent systems and presents a framework and methodology allowing for the development of such systems for real-world applications. The authors focus on applications in financial investment planning and data mining.

An Agent-Based Framework for Complex Problem Solving

Agent-Based Hybrid Intelligent Systems

Hans W. Guesgen

Wai K. Yeap

The Pacific Rim International Conference on Artificial Intelligence (PRICAI) is a biennial international event which focuses on Artificial Intelligence (AI) theories and technologies, and their applications which are of social and economic importance for countries in the Pacific Rim region. Seven earlier conferences were held in: Nagoya, Japan (1990); Seoul, Korea (1992); Beijing, China (1994); Cairns, Australia (1996); Singapore (1998); Melbourne, Australia (2000); and Tokyo, Japan (2002). PRICAI 2004 was the eigth in the series and was held in Auckland, New Zealand in August 2004. PRICAI 2004 had attracted a historical record number of submissions, a total of 356 papers. After careful reviews by at least two international Program Committee members or referees, 94 papers were accepted as full papers (27%) and 54 papers (15%) were accepted as posters. Authors of accepted papers came from 27 countries. This volume of the proceedings contains all the 94 full papers but only a 2-page - tended abstract of each of the accepted posters. The full papers were categorized into four sections, namely: AI foundations, computational intelligence, AI technologies and systems, and AI specific application areas. Among the papers submitted, we found “Agent Technology” to be the area having the most papers submitted. This was followed by “Evolutionary Computing”, “Computational Learning”, and “Image Processing”.

Xindong Wu

The Web has emerged as a large, distributed data repository, and information on the Internet and in existing transaction databases can be analyzed for commercial gains in decision making. Therefore, how to efficiently identify quality knowledge from different data sources uncovers a significant challenge. This challenge has attracted wide interest from both academia and the industry. Knowledge Discovery in Multiple Databases provides a comprehensive introduction to the latest advancements in multi-database mining, and presents a local-pattern analysis framework for pattern discovery from multiple data sources. Based on this framework, data preparation techniques in multiple databases, an application-independent database classification for data reduction, and efficient algorithms for pattern discovery from multiple databases are described. Knowledge Discovery in Multiple Databases is suitable for researchers, professionals and students in data mining, distributed data analysis, and machine learning, who are interested in multi-database mining. It is also appropriate for use as a text supplement for broader courses that might involve knowledge discovery in databases and data mining.

Knowledge Discovery in Multiple Databases

Dickson Lukose

4th Australian Workshop on Distributed Artificial Intelligence, Brisbane, QLD, Australia, July 13, 1998, Proceedings

Multi-Agent Systems. Theories, Languages and Applications

PACIFIC-ASIA CONFERENCE ON KNOWLEDGE DIS

Honghua Dai

Ramakrishnan Srikant

This book constitutes the refereed proceedings of the 8th Pacific-Asia Conference on Knowledge Discovery and Data mining, PAKDD 2004, held in Sydney, Australia in May 2004. The 50 revised full papers and 31 revised short papers presented were carefully reviewed and selected from a total of 238 submissions. The papers are organized in topical sections on classification; clustering; association rules; novel algorithms; event mining, anomaly detection, and intrusion detection; ensemble learning; Bayesian network and graph mining; text mining; multimedia mining; text mining and Web mining; statistical methods, sequential data mining, and time series mining; and biomedical data mining.

8th Pacific-Asia Conference, PAKDD 2004, Sydney, Australia, May 26-28, 2004, Proceedings

Advances in Knowledge Discovery and Data Mining

Due to the popularity of knowledge discovery and data mining, in practice as well as among academic and corporate R&D professionals, association rule mining is receiving increasing attention. The authors present the recent progress achieved in mining quantitative association rules, causal rules, exceptional rules, negative association rules, association rules in multi-databases, and association rules in small databases. This book is written for researchers, professionals, and students working in the fields of data mining, data analysis, machine learning, knowledge discovery in databases, and anyone who is interested in association rule mining.

Models and Algorithms

Association Rule Mining

Longbing Cao

Yanchang Zhao

This book offers state-of the-art research and development outcomes on methodologies, techniques, approaches and successful applications in domain driven, actionable knowledge discovery. It bridges the gap between business expectations and research output.

Domain Driven Data Mining

Chengqi Zhang

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