Dingzhu Du

Frank Hwang

Pooling designs have been widely used in various aspects of DNA sequencing. In biological applications, the well-studied mathematical problem called "group testing" shifts its focus to nonadaptive algorithms while the focus of traditional group testing is on sequential algorithms. Biological applications also bring forth new models not previously considered, such as the error-tolerant model, the complex model, and the inhibitor model. This book is the first attempt to collect all the significant research on pooling designs in one convenient place.The coverage includes many real biological applications such as clone library screening, contig sequencing, exon boundary finding and protein-protein interaction detecting and introduces the mathematics behind it.

Important Tools for DNA Sequencing

Pooling Designs and Nonadaptive Group Testing

Convergence Theory of Feasible Direction Methods

Panos M. Pardalos

Peng-Jun Wan

Time division multiplexing (TDM) has been the fundamental basis for adding capacity to digital telecommunications networks for decades. However, within the past two years, wavelength division multiplexing (WDM) has been emerging as an important and widely deployed complement to TDM. Sales of systems based on the new technology have risen at breathtaking speed. The driving force behind this sales explosion was the unexpected rapid exhaustion of long distance fiber network capacity. This fiber exhaust, combined with favorable economics for WDM, led to the use of this technology over other alternatives. The WDM deployment raises fundamental and challenging problems that require novel and innovative solutions. This volume presents papers from an interdisciplinary workshop held at DIMACS on multichannel optical networks. Leading computer science theorists and practitioners discussed admissions control, routing and channel assignment, multicasting and protection, and fault-tolerance. The book features application of theoretical and/or algorithmical results to practical problems and addresses the influence of practical problems to theoretical/algorithmic studies. The volume can serve as a text for an advanced course in computer science, networking, and operations research.

Theory and Practice : DIMACS Workshop, March 16-19, 1998

Multichannel Optical Networks

Liqun Qi

Robert S. Womersley

Nonsmooth optimization covers the minimization or maximization of functions which do not have the differentiability properties required by classical methods. The field of nonsmooth optimization is significant, not only because of the existence of nondifferentiable functions arising directly in applications, but also because several important methods for solving difficult smooth problems lead directly to the need to solve nonsmooth problems, which are either smaller in dimension or simpler in structure.This book contains twenty five papers written by forty six authors from twenty countries in five continents. It includes papers on theory, algorithms and applications for problems with first-order nondifferentiability (the usual sense of nonsmooth optimization) second-order nondifferentiability, nonsmooth equations, nonsmooth variational inequalities and other problems related to nonsmooth optimization.

Recent Advances in Nonsmooth Optimization

Xiaotie Deng

This book constitutes the refereed proceedings of the 16th International Symposium on Algorithms and Computation, ISAAC 2005, held in Sanya, Hainan, China in December 2005. The 112 revised full papers presented were carefully reviewed and selected from 549 submissions. The papers are organized in topical sections on computational geometry, computational optimization, graph drawing and graph algorithms, computational complexity, approximation algorithms, internet algorithms, quantum computing and cryptography, data structure, computational biology, experimental algorithm mehodologies and online algorithms, randomized algorithms, parallel and distributed algorithms, graph drawing and graph algorithms, computational complexity, combinatorial optimization, computational biology, computational complexity, computational optimization, computational geometry, approximation algorithms, graph drawing and graph algorithms, computational geometry, approximation algorithms, graph drawing and graph algorithms, and data structure.

16th International Symposium, ISAAC 2005, Sanya, Hainan, China, December 19-21, 2005, Proceedings

Algorithms and Computation

This book is a collection of surveys and exploratory articles about recent developments in the field of computational Euclidean geometry. The topics covered are: a history of Euclidean geometry, Voronoi diagrams, randomized geometric algorithms, computational algebra; triangulations, machine proofs, topological designs, finite-element mesh, computer-aided geometric designs and steiner trees. Each chapter is written by a leading expert in the field and together they provide a clear and authoritative picture of what computational Euclidean geometry is and the direction in which research is going.

Computing in Euclidean Geometry

Combinatorial (or discrete) optimization is one of the most active fields in the interface of operations research, computer science, and applied math ematics. Combinatorial optimization problems arise in various applications, including communications network design, VLSI design, machine vision, air line crew scheduling, corporate planning, computer-aided design and man ufacturing, database query design, cellular telephone frequency assignment, constraint directed reasoning, and computational biology. Furthermore, combinatorial optimization problems occur in many diverse areas such as linear and integer programming, graph theory, artificial intelligence, and number theory. All these problems, when formulated mathematically as the minimization or maximization of a certain function defined on some domain, have a commonality of discreteness. Historically, combinatorial optimization starts with linear programming. Linear programming has an entire range of important applications including production planning and distribution, personnel assignment, finance, alloca tion of economic resources, circuit simulation, and control systems. Leonid Kantorovich and Tjalling Koopmans received the Nobel Prize (1975) for their work on the optimal allocation of resources. Two important discover ies, the ellipsoid method (1979) and interior point approaches (1984) both provide polynomial time algorithms for linear programming. These algo rithms have had a profound effect in combinatorial optimization. Many polynomial-time solvable combinatorial optimization problems are special cases of linear programming (e.g. matching and maximum flow). In addi tion, linear programming relaxations are often the basis for many approxi mation algorithms for solving NP-hard problems (e.g. dual heuristics)."

Handbook of combinatorial optimization

Dachuan Xu

Donglei Du

This book constitutes the refereed proceedings of the 21st International Conference on Computing and Combinatorics, COCOON 2015, held in Beijing, China, in August 2015. The 49 revised full papers and 11 shorter papers presented were carefully reviewed and selected from various submissions. The papers cover various topics including algorithms and data structures; algorithmic game theory; approximation algorithms and online algorithms; automata, languages, logic and computability; complexity theory; computational learning theory; cryptography, reliability and security; database theory, computational biology and bioinformatics; computational algebra, geometry, number theory, graph drawing and information visualization; graph theory, communication networks, optimization and parallel and distributed computing.

21st International Conference, COCOON 2015, Beijing, China, August 4-6, 2015, Proceedings

Computing and Combinatorics

The first of a multi-volume set, which deals with several algorithmic approaches for discrete problems as well as many combinatorial problems. It is addressed to researchers in discrete optimization, and to all scientists who use combinatorial optimization methods to model and solve problems.

Handbook of combinatorial optimization. 1

Jie Wang

This volume presents selected papers from a three-day workshop held during the DIMACS special years on Mathematical Support for Molecular Biology. Participants from the world over attended, giving the workshop an important international component. The study of discrete mathematics and optimization with medical applications is emerging as an important new research area. Significant applications have been found in medical research, for example in radiosurgical treatment planning, virtual endoscopy, and more. This volume presents a substantive cross-section of active research topics ranging from medical imaging to human anatomy modeling, from gamma knife treatment planning to radiation therapy, and from epileptic seizures to DNA screening. This book is an up-to-date resource reflecting current research directions.

DIMACS Workshop Discrete Mathematical Problems with Medical Applications, December 8-10, 1999, DIMACS Center

Discrete Mathematical Problems with Medical Applications

Xiaodong Hu

The Steiner tree problem is one of the most important combinatorial optimization problems. It has a long history that can be traced back to the famous mathematician Fermat (1601-1665). This book studies three significant breakthroughs on the Steiner tree problem that were achieved in the 1990s, and some important applications of Steiner tree problems in computer communication networks researched in the past fifteen years. It not only covers some of the most recent developments in Steiner tree problems, but also discusses various combinatorial optimization methods, thus providing a balance between theory and practice.

Dingzhu Du

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