Liehuang Zhu

Fei Yan

Weili Han

This book constitutes the refereed proceedings of the Chinese Conference on Trusted Computing and Information Security, CTCIS 2019, held in Shanghai, China, in October 2019. The 22 revised full papers presented were carefully reviewed and selected from 247 submissions. The papers are centered around cryptography, systems security, trusted computing, information security, network security, information hiding.

13th Chinese Conference, CTCIS 2019, Shanghai, China, October 24–27, 2019, Revised Selected Papers

Trusted Computing and Information Security

Ming Xu

Zheng Qin

Shaojing Fu

This book constitutes the refereed proceedings of the 11th Chinese Conference on Trusted Computing and Information Security, CTCIS 2017, held in Changsha, China, in September 2017. The 28 revised full papers presented were carefully reviewed and selected from 96 submissions. The papers focus on topics such as theory of trusted computing, trustworthy software; infrastructure of trusted computing, application and evaluation of trusted computing; network security and communication security; theory and technology of cryptographic techniques; information content security; system security for mobile network and IoT systems, industrial control and embedded systems; security for Cloud computing, virtualization systems and big data.

11th Chinese Conference, CTCIS 2017, Changsha, China, September 14-17, 2017, Proceedings

Xiaobing Wang

Jean Jose

Precision medicine is an approach that proposes customized medical care based on the individual characteristics of each patient. The rapidly emerging field not only holds great promise for diagnosis of disease and prediction of risk of developing diseases, but also offers the possibility of remarkably fine-tuned remedies to improve patient health while minimizing the risk of harmful side effects. Many technologies including genetics, informatics, and medical imaging, are rapidly expanding the scope of precision medicine. Among these technologies, imaging is poised to play a major role in the age of precision medicine. By characterizing anatomy, physiology and metabolism of the patient, medical imaging enables precise, personalized procedures and predictive, patient-specific therapy selection. In recent years, image-guided treatment procedures are becoming more and more common in hospitals, replacing conventional surgery or allowing faster recoveries with fewer post-procedure complications. As the most widely used modality, ultrasound is playing an increasingly important role towards moving precision medicine into clinical practice. It is a safe, inexpensive diagnostic tool and capable of producing real-time and non-invasive images without significant biological effects. To date, lots of ultrasound imaging technology, such as gray-scale, color Doppler flow imaging (CDFI), contrast enhanced ultrasound (CEUS), elastography have been developed, which have greatly improved disease diagnosis, treatment and prognosis. Thanks to these progress, ultrasound imaging has also been used in fields that were not previously involved, such as the lungs and musculoskeletal tissues. With the rapid development of ultrasound contrast agents, ultrasound molecular imaging is moving from animal study into clinical practice. First-in-human results of ultrasound molecular imaging with BR55 (a kinase insert domain receptor [KDR]–targeted contrast microbubble) in patients with breast and ovarian lesions have been reported in 2017. Taking advantage of microbubble cavitation effect, ultrasound-assisted drug delivery technology also makes great progress. The clinical trial of blood-brain barrier disruption for chemotherapy delivery in the brain had been conducted and confirmed its safety and well toleration in patients with recurrent glioblastoma (GBM). Moreover, ultrasound provides an advantageous tool for image-guided therapy due to its capability of real-time imaging for deep tissues, contributing to greatly improved localization and targeting of diseased tissues. More interestingly, by imaging these drug-loaded contrast agents, ultrasound-mediated drug delivery can be visualized. All of the above examples help demonstrate the promising potential of ultrasound in precision medicine, not only for disease diagnosis, but also for treatment selection and prognosis evaluation. The present Research Topic here in Frontiers in Pharmacology aims to bring a collection of research describing ultrasound used for precision medicine in diagnosis, drug delivery and image-guided therapy.

Ultrasound for Precision Medicine: Diagnosis, Drug Delivery and Image-Guided Therapy

Salvador E. Venegas-Andraca

This book provides a comprehensive introduction to quantum image processing, which focuses on extending conventional image processing tasks to the quantum computing frameworks. It summarizes the available quantum image representations and their operations, reviews the possible quantum image applications and their implementation, and discusses the open questions and future development trends. It offers a valuable reference resource for graduate students and researchers interested in this emerging interdisciplinary field.

Fei Yan

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