Frederick R. Sidell

Timothy C. Marrs

Robert L. Maynard

This book is an accessible and authoritative guide to the practical medical management of victims of chemical warfare and offers an explanation of the underlying pharmacology and toxicology of the various agents. It discusses all major classical chemical warfare agents including nerve agents, vesicants, lung damaging agents, respiratory poisons, irritants and psychoactive agents covering the toxicology, pharmacology, human studies and treatment options for each class. Also features a section on field management of chemical agent exposure.

Toxicology and Treatment

Chemical Warfare Agents

William C. Patrick

Thomas R. Dashiell

Jane's Chem-bio Handbook

EDGEWOOD ARSENAL ABERDEEN PROVING GROUND MD.

The case histories of five patients accidentally exposed to anticholinesterase compounds (sarin or soman) are presented. The circulating cholinesterase of one patient severely exposed to soman was refractory to oxime reactivation; this patient also had psychological sequelae which were ameliorated by scopolamine. In three patients who had mild manifestations of sarin intoxication the initial rate of recovery of plasma cholinesterase paralleled the recovery of their ability for adaptation to the dark, or loss of miosis. An anticholinergic compound with high central nervous system affinity, such as scopolamine, should be tried further when psychological morbidity follows anticholinesterase compound intoxication. (Author).

Sarin and Soman: Observations on Accidental Exposures

Frederick R. Sidell

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