Debasis Bagchi

Harry G. Preuss

Divided into four main sections, Dietary Sugar, Salt and Fat in Human Health explores the biochemical, pharmacological and medicinal aspects related to the overindulgence of dietary salt, sugar, and fat, along with possible remedies. Beginning with a general overview, the text outlines aspects associated with advancing age and human physiology, such as different aspects of insulin resistance, the advancing age phenomenon, central fat accumulation and metabolic perturbations and the role of the modern Western diet and the influence of dietary sugar, salt, and fat, with particular focus on their relation to multiple biochemical pathophysiological pathways. The second section of the book focuses on the roles of dietary sugars and their correlation with the chronic disease epidemic, with an emphasis on carbohydrate metabolism and its biochemistry, GI absorption, the glycemic index and the influence of fructose. The historical background of dietary sugars is discussed alongside Atkin’s hypothesis, and an overview of the correlation between dietary fibre and the glycemic index, including a chapter on sugar addiction. Section three contains an exhaustive review of the influence of dietary salt and its diverse mechanistic aspects, including salt-sensitive hypertension, contribution of two steroid receptor pathways, vascular NO, intrarenal RAAS system and angiotensin. The fourth section highlights the biochemistry of dietary saturated, polyunsaturated and trans fat and its influence on human health and various diseases, and further explores NAFLD and gender specific problems. Chapters in this section also investigate the benefits of the Mediterranean diet as well as myths related to cholesterol. Collected and carefully organized for researchers in nutrition, physiology, epidemiology, or sensory science, this book will also benefit general practitioners, surgeons, nurses, health professionals and practitioners, and students studying the role of diet in cardiometabolic disorders and disease. Demonstrates how a healthy lifestyle impacts lifespan Provides a general overview and outlines aspects associated with advancing age and human physiology Focuses on the roles of dietary sugars and their correlation with the chronic disease epidemic Contains an exhaustive review of the influence of dietary salt and its diverse mechanistic aspects Highlights the biochemistry of dietary saturated, polyunsaturated and trans fat and its influence on human health and various diseases

Dietary Sugar, Salt and Fat in Human Health

During the past decade, a significant amount of research has been conducted on phytopharmaceuticals. Today, a growing body of evidence demonstrates the efficacy of a wide variety of natural products and affirms their potential in the treatment of cancer. Phytopharmaceuticals in Cancer Chemoprevention focuses on the role of natural supplemen

Phytopharmaceuticals in Cancer Chemoprevention

Joan Ifland

Marianne T. Marcus

Obesity and eating disorders have stubbornly refused to respond to treatment since the 1990’s. This book organizes the evidence for a possible answer, i.e., that the problem could be one of addiction to processed foods. In a Processed Food Addiction (PFA) model, concepts of abstinence, cue-avoidance, acceptance of lapses, and consequences all play a role in long-term recovery. Application of these concepts could provide new tools to health professionals and significantly improve outcomes. This book describes PFA recovery concepts in detail. The material bridges the research into practical steps that health professionals can employ in their practices. It contains an evidence-based chapter on concepts of abstinence from processed foods. It rigorously describes PFA pathology according to the DSM 5 Addiction Diagnostic Criteria. It applies the Addiction Severity Index to PFA so that health practitioners can orient themselves to diagnosing and assessing PFA. It contains ground-breaking insight into how to approach PFA in children. Because the book is evidence-based, practitioners can gain the confidence to put the controversy about food addiction to rest. Practitioners can begin to identify and effectively help their clients who are addicted to processed foods. This is a breakthrough volume in a field that could benefit from new approaches.

Foundations, Assessment, and Recovery

Processed Food Addiction

The World Health Organization (WHO) has declared obesity a global epidemic. Its prevalence has more than doubled since 1980, causing a myriad of health problems for children and adults. Obesity: Epidemiology, Pathophysiology, and Prevention, Second Edition explores the molecular mechanisms and pathophysiology leading to obesity and metabolic disorders. It examines the safety of obesity drugs and drug development strategies as well as the role of physical activity, nutrition, and nutraceutical supplements in obesity treatment and prevention. With contributions from a cadre of internationally known experts, the book covers a spectrum of essential topics related to this widespread phenomenon, including: The relationship between obesity and type 2 diabetes The addiction mechanism related to refined foods as a significant factor in obesity The correlation between obesity and environmental estrogens, endocrine disruption, cigarette smoking, and inflammatory response The role of drug and chemical toxicities and genomic imprinting disorders in obesity The safety and regulation of prescription and over-the-counter weight loss drugs Various diets, the glycemic index, and the role of exercise in treating or preventing obesity Controversy over effective vs. banned weight loss supplements Childhood obesity and its prevention Bariatric surgery for weight management and reversal of metabolic disorders As the public has become more aware of the deadly adverse effects of obesity, numerous products and programs have targeted the overweight and obese population, many with dangerous side effects. It is essential that we develop strategic, therapeutic intervention supported by credible data. This volume is an ideal reference point for researchers looking for new avenues of inquiry and practicing medical professionals, clinical nutritionists, and dietitians seeking guidance for their patients.

Harry G. Preuss

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