Jack D. Maser

Martin B. Keller

William H. Coryell

Jean Endicott

Pamela J. Schettler

Conceived in the early 1970s to study the phenomenology, diagnosis, genetics, and clinical course of depression, the NIMH Collaborative Depression Study (CDS) has influenced research and practice since its inception. Clinical Guide to Depression and Bipolar Disorder: Findings From the Collaborative Depression Study summarizes key findings from the study and the related literature to provide comprehensive and up-to-date knowledge on the course and outcome of illness in mood disorders. Nowhere else can clinicians find such detailed longitudinal data, combined with astute clinical analysis of the current research. The volume offers: Historical background on how psychodynamic psychiatry was overtaken by psychobiological perspectives, and the challenges and controversies that gave rise to the CDS, providing the context necessary to understand the profession's development to the present day. A wealth of information on nosology, natural history, phenomenology, and treatment response in depressive and bipolar disorders. Detailed descriptions of the study methods employed, providing information and insights that will assist researchers in the longitudinal design of prospective cohort studies. Comprehensive review of outcomes in mood disorder, including delineation of the long-term course of bipolar I, bipolar II, and unipolar major depressive disorders, the implications of which will continue to be instrumental in the development of psychiatric nosology and indispensable to clinicians engaged in assessment and treatment. Critical information clinicians need in order to read the clinical signs in their patients and predict the "switch" from unipolar to bipolar disorder. A fascinating review of the evolution of diagnostic thinking about the role of anxiety in mood disorders, and the contributions of the CDS to the newly published DSM-5®. Each chapter is accompanied by a time-saving summary, as well as a section on clinical implications that translates the findings into practical points and key recommendations clinicians need to know to provide optimal care. Psychiatrists, clinical psychologists, residents, and fellows will turn to Clinical Guide to Depression and Bipolar Disorder: Findings From the Collaborative Depression Study to better understand the course and outcome of their patients' mood disorders and, ultimately, to improve their clinical skills.

Findings From the Collaborative Depression Study

Clinical Guide to Depression and Bipolar Disorder

C. Robert Cloninger

The book brings together information about psychiatric comorbidity, and presents a systematic examination of the co-occurrence of different symptoms and syndromes in patients with disorders of anxiety or mood.

Comorbidity of Mood and Anxiety Disorders

The clinical interview is an indispensable first step in a comprehensive general medical evaluation. In psychiatry and clinical psychology, it is too frequently the only step in the evaluation. Based on papers presented at an National Institute of Mental Health sponsored workshop, this volume specifically addresses the question of whether the clinical phenomenology necessary for diagnosis of mental disorders can be assessed in ways more objective and accurate than routine clinical observation.

Depression and Expressive Behavior

S. Rachman

The topic of panic has been dominated by biological studies in many areas of anxiety research. This collection of papers, resulting from the National Institute of Mental Health Conferences, presents the viewpoints of clinical researchers assessing the state of the anxiety field. Contributors to this volume argue that biological data can be encompassed in psychological theory.

Jack D. Maser

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