Howard I. Maibach

Hongbo Zhai

Klaus Peter Wilhelm

The foundational reference in dermal toxicology, this classic text has been completely revised to bring it up to date in the new Eighth Edition, with almost a third of its chapters being newly added. The structure of the text has also been reorganized to enable easier location of a topic of interest. With contributions from leading international experts, this continues the tradition of providing unsurpassed theoretical and practical guidance for all those working on research aspects, on practical clinical issues, and on the regulatory aspects of exposure to toxic substances. This new edition contains updates to each chapter and contributions from leading international experts, provides an in-depth summary of research and regulatory applications related to dermal toxicology and pharmacology, presents many new chapters that describe the latest advances in dermatotoxicology, and addresses various levels of expertise regarding the development and use of dermal exposure data. New chapters include those on safety terminology, pharmacogenetics and dermatology, ethnic differences in skin properties, and the principles and practice of percutaneous absorption.

Dermatotoxicology, Eighth Edition

Reflecting the embryonic state of the field, the first edition of Dermatoxicology, published in 1977, numbered 567 pages. Now the foundational reference in dermal toxicology, this seventh edition consists of 1,032 pages and defines what was once a largely intuitive field but has evolved into an established science of metrics and mechanisms. Updated and expanded to reflect the latest developments, the seventh edition includes fundamental information on the mechanisms of action of toxic substances on the skin and practical information on the many methods for evaluating dermal toxicity. Unparalleled in its coverage and broad in scope, with the addition of 34 new chapters, this volume keeps pace with the expanding science. A perennial bestseller, this definitive text explores the latest developments in the field. With contributions from leading international experts, it continues the tradition of providing unsurpassed theoretical and practical guidance.

Klaus Peter Wilhelm

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