Yi-Wei Tang

David H. Persing

Fred C. Tenover

Randall T. Hayden

Margareta Ieven

Melissa B. Miller

Frederick S. Nolte

Alex van Belkum

Presenting the latest molecular diagnostic techniques in one comprehensive volume The molecular diagnostics landscape has changed dramatically since the last edition of Molecular Microbiology: Diagnostic Principles and Practice in 2011. With the spread of molecular testing and the development of new technologies and their opportunities, laboratory professionals and physicians more than ever need a resource to help them navigate this rapidly evolving field. Editors David Persing and Fred Tenover have brought together a team of experienced researchers and diagnosticians to update this third edition comprehensively, to present the latest developments in molecular diagnostics in the support of clinical care and of basic and clinical research, including next-generation sequencing and whole-genome analysis. These updates are provided in an easy-to-read format and supported by a broad range of practical advice, such as determining the appropriate type and quantity of a specimen, releasing and concentrating the targets, and eliminating inhibitors. Molecular Microbiology: Diagnostic Principles and Practice Presents the latest basic scientific theory underlying molecular diagnostics Offers tested and proven applications of molecular diagnostics for the diagnosis of infectious diseases, including point-of-care testing Illustrates and summarizes key concepts and techniques with detailed figures and tables Discusses emerging technologies, including the use of molecular typing methods for real-time tracking of infectious outbreaks and antibiotic resistance Advises on the latest quality control and quality assurance measures Explores the increasing opportunities and capabilities of information technology Molecular Microbiology: Diagnostic Principles and Practice is a textbook for molecular diagnostics courses that can also be used by anyone involved with diagnostic test selection and interpretation. It is also a useful reference for laboratories and as a continuing education resource for physicians. If you are looking for online access to the latest clinical microbiology content, please visit www.wiley.com/learn/clinmicronow.

Diagnostic Principles and Practice

Molecular Microbiology

Peter H. Gilligan

Daniel S. Shapiro

Cases in Medical Microbiology and Infectious Diseases challenges students to develop a working knowledge of the variety of microorganisms that cause infections in humans. This valuable, interactive text will help them better understand the clinical importance of the basic science concepts presented in medical microbiology or infectious disease courses. The cases are presented as "unknowns" and represent actual case presentations of patients the authors have encountered. Each case is accompanied by several questions to test knowledge in four broad areas including the organism's characteristics and laboratory diagnosis; pathogenesis and clinical characteristics of the infection; epidemiology; and prevention and, in some cases, drug resistance and treatment. This new fourth edition includes: an entirely new section, "Advanced Cases," which includes newly recognized disease agents as well as highly complex cases where the interaction of the immune system and human pathogens can be more closely examined a revised "Primer on the Laboratory Diagnosis of Infectious Diseases" section that reflects the increasing importance of molecular-based assays Forty-two new cases that explore the myriad advances in the study of infectious disease in the past decade Thirty-two updated cases that reflect the current state of the art as it relates to the organism causing the infection This textbook also include specific tools to assist students in solving the cases, including a table of normal values, glossary of medical terms, and figures illustrating microscopic organism morphology, laboratory tests, and clinical symptoms. Cases in Medical Microbiology and Infectious Diseases is a proven resource for preparing for Part I of the National Board of Medical Examiners Exam and an excellent reference for infectious disease rotations.

Cases in Medical Microbiology and Infectious Diseases

Presenting the latest molecular diagnostic techniques in one comprehensive volume The molecular diagnostics landscape has changed dramatically since the last edition of Molecular Microbiology: Diagnostic Principles and Practice in 2011. With the spread of molecular testing and the development of new technologies and their opportunities, laboratory professionals and physicians more than ever need a resource to help them navigate this rapidly evolving field. Editors David Persing and Fred Tenover have brought together a team of experienced researchers and diagnosticians to update this third edition comprehensively, to present the latest developments in molecular diagnostics in the support of clinical care and of basic and clinical research, including next-generation sequencing and whole-genome analysis. These updates are provided in an easy-to-read format and supported by a broad range of practical advice, such as determining the appropriate type and quantity of a specimen, releasing and concentrating the targets, and eliminating inhibitors. Molecular Microbiology: Diagnostic Principles and Practice Presents the latest basic scientific theory underlying molecular diagnostics Offers tested and proven applications of molecular diagnostics for the diagnosis of infectious diseases, including point-of-care testing Illustrates and summarizes key concepts and techniques with detailed figures and tables Discusses emerging technologies, including the use of molecular typing methods for real-time tracking of infectious outbreaks and antibiotic resistance Advises on the latest quality control and quality assurance measures Explores the increasing opportunities and capabilities of information technology Molecular Microbiology: Diagnostic Principles and Practice is a textbook for molecular diagnostics courses that can also be used by anyone involved with diagnostic test selection and interpretation. It is also a useful reference for laboratories and as a continuing education resource for physicians.

Melissa B. Miller

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