Paul D. Boyer

Feng Guo

Chentao Lin

Fuyuhiko Tamanoi

David D. Hackney

Channing J. Der

Yasunori Machida

Sheng Luan

Michael N. Hall

Edwin G. Krebs

D. S. Sigman

Ross E. Dalbey

Steven G. Clarke

Carla M. Koehler

Anant Kumar Menon

Christine A. Hrycyna

Martin O. Bergo

Tony Y. Hu

S. Zahra Bathaie

Keizō Inoue

Diana M. Stafforini

The Enzymes

George Thomas

David M. Sabatini

TOR, the Target of Rapamycin was discovered a little over ten years ago in a genetic screen in S. cerevisiae in search of mutants resistant to the cytostatic effects of the antimycotic, rapamycin. Recent studies have placed TOR at the interface between nutrient sensing and the regulation of major anbolic and catabolic responses. The editors have gathered the leading figures in the field of TOR and its role in cellular homeostasis and human diseases.

Target of Rapamycin

Michael N. Hall

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