Michael P. Manns

Thomas D. Boyer

Theresa L. Wright

Zakim and Boyer’s Hepatology—the defining work in hepatology—presents comprehensive coverage of both basic science and clinically relevant developments so you can provide the best possible patient care. Drs. Thomas Boyer, Michael Manns, and Arun Sanyal have reorganized and updated the contents of this trusted global reference to reflect today’s more clinical approach to hepatology. They bring you up to date on hot topics including HIV Co-Infection Drug Toxicity, Hepatocellular Carcinoma (HCC), and much more. This new streamlined edition is now a single volume making it easier to find the treatment information you need. Effectively treat all liver diseases currently seen in clinical practice with authoritative guidance from leading international authorities. Reinforce your foundation in basic science with the concise Pathophysiology of Therapeutic Targets section. See clear presentations of liver disease through hundreds of detailed, color illustrations. Explore topics further with up-to-date references that direct you to the significant literature. Stay current on new developments in the field through five new chapters on Pathogenesis Liver Injury in HBV, HCV; HCC; Imaging and Non-Invasive DX Liver Disease CT, US, Fibroscan, MRI; HIV Co-Infection Drug Toxicity; and HBC, HCV in Non-Liver Transplant Patients, plus comprehensive updates throughout. Apply best practices with reorganized and updated content that reflects today’s need for a more clinical approach to hepatology.

A Textbook of Liver Disease

Zakim and Boyer's Hepatology E-Book

Michael Fried

Gerhard Rogler

Seit 2007 gibt es den Modellstudiengang Medizin an den Hochschulen in Aachen, Berlin, Bochum, Hannover, Heidelberg, Köln, Witten und Göttingen. Die in 17 Themenblöcke gegliederte Lehre folgt der Approbationsordnung für Ärzte, die Prüfungen sind den einzelnen Modulen zugeordnet. Das Lehrbuch Gastroenterologie ist das erste Buch zum Lernen im Modul. Gut verständlich wird das gesamte Organsystem dargestellt: von der Anatomie bis zur Therapie. Das Buch ist geeignet für Medizinstudenten und für Ärzte in der Aus- und Weiterbildung.

Magen-Darm-Trakt

Kerstin Anne Stegmann

Heiner Wedemeyer

Implications for Hepatitis C Virus Infection

Effects of IFN[alpha] [IFN-alpha] on Human NK Cells

Atsushi Tanaka

M. Eric Gershwin

John M. Vierling

The third edition of this acclaimed work provides clinicians and investigators with a wealth of state-of-the-art information that will lead to fresh approaches in thinking about liver physiology and liver diseases. Developed by a panel of renowned international authors, this edition outlines a range of important advances in our understanding of the liver’s role as an immune organ and the functions of innate and adaptive immunity in the pathogenesis of all liver diseases. Indeed, the liver is a vitally important immune organ producing liver-derived products that can trigger the innate and adaptive immune system to initiate, mediate, regulate, and resolve systemic inflammation. The book begins with an analysis of the core concepts of immunology, including the definition of autoimmunity and its unique application to the liver, a tolerogenic organ. Subsequent chapters then explore the biological elements of liver diseases caused by epigenetics, genetics, and innate and adaptive immunity. Specific clinical presentations and aspects of liver diseases are also examined, such as Hepatitis C, non-alcoholic fatty liver disease and parasitic infections. Closing chapters then discuss liver diseases among specific populations, including pediatrics, those with comorbidities and preexisting conditions, pregnant women, and finally patients with transplanted organs. A timely and invaluable update to the clinical literature, Liver Immunology: Principles and Practice, Third Edition, is once again a comprehensive work that will not only enhance the understanding of liver diseases but also provide the kind of novel insights that greatly accelerates the evidence-based care of children and adults afflicted with these diseases. This volume is again a must-read for clinicians at all levels, for investigators and for students.

Principles and Practice

Liver Immunology

Michael P. Manns

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