Mohammad Shenasa

Stanley Nattel

This issue of Cardiac Electrophysiology Clinics, edited by Drs. Mohammad Shenasa and Stanley Nattel, will review Cardiac Potassium Channel Disorders in depth. Topics covered include but are not limited to: Molecular Biology of Cardiac Potassium Channels; Genetic Control of Potassium Channels; Potassium Channel Remodeling in Heart Disease; Gender-specific Effects of Potassium Channel Blockers; Pharmacogenetics of Potassium Channel Blockers; Multichannel Blockers; Selective Potassium Channel Blockers; and Proarrhythmic and Torsadogenic Effects of Potassium Channel Blockers in Patients.

Cardiac Potassium Channel Disorders, An Issue of Cardiac Electrophysiology Clinics

Edward P. Walsh

George F. Van Hare

Paul Khairy

This authoritative book explores electrophysiologic testing and therapeutic catheter ablation for cardiac arrhythmias in children, and in patients of all ages with congenital heart disease. It reviews the anatomic and physiologic background to these procedures, emphasizing the tools for mapping and tissue ablation that continue to improve patient outcomes. Additionally, individual chapters are dedicated to specific congenital heart defects (for instance, tetralogy of Fallot, Ebstein’s anomaly, univentricular heart) guiding the reader to anticipate the type of arrhythmia, the most likely location for effective ablation, and the technical challenges that may be encountered in each condition. Key Features Provides a detailed review of the unique challenges presented by young patients with small heart size, and patients of any age with distorted anatomy due to congenital heart disease, in this long overdue, updated text Intends to guide all cardiologists engaged in invasive electrophysiology at both the training level and established practice who are exposed to such exceptional cases Includes an internationally recognized group of experts who discuss the technical approaches, success rates, complication rates, and special precautions needed to achieve optimal outcomes

Catheter Ablation of Cardiac Arrhythmias in Children and Patients with Congenital Heart Disease

Martin Borggrefe

Mark E. Josephson

Gerhard Hindricks

Gunter Breithardt

Cardiac Mapping is the cardiac electrophysiologist’s GPS. It will guide you to new places in the heart and help you find the old places more easily...a valuable addition to your bookshelf Douglas P. Zipes, from the Foreword. Over the course of three previous editions, this book has become the acknowledged gold standard reference on the electro-anatomical mapping of the heart. This new edition features greatly expanded coverage—the number of chapters have doubled to 80 with 40 new chapters—on leading edge science, new clinical applications and future frontiers, authored by a who’s-who of global electrophysiology. This unique text offers truly comprehensive coverage of all areas of cardiac mapping, from core scientific principals to methodological and technical considerations to the latest data that you can put to work caring for patients. In addition, the all new 4th edition adds essential content on: Mapping in experimental models of arrhythmias Mapping supraventricular and ventricular tachyarrhythmias New catheter-based techniques Also featuring a companion website with video clips illustrating essential techniques described in the text The only state-of-the-art, stand-alone text on this dynamic subject, Cardiac Mapping is an essential resource for basic scientists, clinical electrophysiologists, cardiologists and all physicians who care for patients with cardiac arrhythmias.

Cardiac Mapping

Prashanthan Prashanthan

This issue of Cardiac Electrophysiology Clinics, Guest Edited by Drs. Mohammad Shenasa, Prashanthan Sanders, and Stanley Nattel, is dedicated to Risk Factors in Atrial Fibrillation: Appraisal of AF Risk Stratification. This is one of four issues selected each year by the series Consulting Editors, Ranjan K. Thakur and Andrea Natale. Topics include, but are not limited to, Epidemiology of Atrial Fibrillation; Hypertension, Prehypertension, Hypertensive Heart Disease and Atrial Fibrillation; Pulmonary Disease, Pulmonary Hypertension and Atrial Fibrillation; Heart Failure with Preserved (HFpEF) and Reduced (HFrEF) LV Systolic Function, Diastolic Dysfunction; Coronary Artery Disease; ECG and Echo Abnormalities in Patients with Atrial Fibrillation Risk Factors; Diabetes and Endocrine Disorders; Obesity and Metabolic Syndrome in Atrial Fibrillation; Renal Disease; Sleep Apnea and Atrial Fibrillation; Channelopathies in Atrial Fibrillation; Implications of Inflammation and Myocardial Fibrosis in Atrial Fibrillation; Role of Biomarkers in Atrial Fibrillation; Left Ventricular Hypertrophy and Other Cardiomyopathies in Atrial Fibrillation; Atrial Fibrillation in Valvular Heart Disease; Atrial Fibrillation in Adult Congenital Heart Disease; Exercise and Athletic Activity in Atrial Fibrillation; Post-op Atrial Fibrillation; Autonomic Dysfunction and Neurohormonal Disorders in Atrial Fibrillation; Social Risk Factors; Atrial Fibrillation and Stroke; Screening for Atrial Fibrillation Risk Factors; Primary Care and Internists Perspective on Atrial Fibrillation Risk Factors; and Lifestyle as a Risk Factor for Atrial Fibrillation.

Risk Factors in Atrial Fibrillation: Appraisal of AF Risk Stratification, An Issue of Cardiac Electrophysiology Clinics, E-Book

Risk Factors in Atrial Fibrillation: Appraisal of AF Risk Stratification, an Issue of Cardiac Electrophysiology Clinics, Volume 13-1

Amin Al-Ahmad

This issue of Cardiac Electrophysiology Clinics, guest edited by Mohammad Shenasa and Amin Al-Ahmad, will focus on Advances in Cardiac Mapping and Catheter Ablation. This is part one of a two-part issue and will include articles centered around Basic Concepts in Cardiac Mapping, Novel Mapping & Imaging Systems & Technologies, and Catheter and Energy Sources. Topics include, but are not limited to, Embryology of the Cardiac Conduction System Relevant to Cardiac Arrhythmias; Anatomical Consideration Relevant to Atrial and Ventricular Arrhythmias; Fundamentals of Cardiac Mapping; Novel Cardiac Mapping Systems; Non-invasive Mapping & ECGI in Atrial and Ventricular Arrhythmias; Optical Mapping; Omnipolar Mapping; Cardiac CT, MRI, and Fibrosis Quantification; High resolution mapping in patients with atrial and ventricular arrhythmias; Contact Force and Ablation Index; and New Catheter Balloons Including Radiofrequency.

Advances in Cardiac Mapping and Catheter Ablation: Part I, An Issue of Cardiac Electrophysiology Clinics

John M. Miller

David J. Callans

The expanded guide to cardiac mapping The effective diagnosis and treatment of heart disease may vitally depend upon accurate and detailed cardiac mapping. However, in an era of rapid technological advancement, medical professionals can encounter difficulties maintaining an up-to-date knowledge of current methods. This fifth edition of the much-admired Cardiac Mapping is, therefore, essential, offering a level of cutting-edge insight that is unmatched in its scope and depth. Featuring contributions from a global team of electrophysiologists, the book builds upon previous editions' comprehensive explanations of the mapping, imaging, and ablation of the heart. Nearly 100 chapters provide fascinating accounts of topics ranging from the mapping of supraventricular and ventriculararrhythmias, to compelling extrapolations of how the field might develop in the years to come. In this text, readers will find: Full coverage of all aspects of cardiac mapping, and imaging Explorations of mapping in experimental models of arrhythmias Examples of new catheter-based techniques Access to a companion website featuring additional content and illustrative video clips Cardiac Mapping is an indispensable resource for scientists, clinical electrophysiologists, cardiologists, and all physicians who care for patients with cardiac arrhythmias.

Günter Breithardt

John A. Camm

The past 10 years have seen a remarkable change in the approach to cardiac arrhythmias, from a position of confidence and a feeling of well-being about pharmacological treatment to a situation in which there is now marked uncertainty and general apprehension about the role of antiarrhythmic drugs. Until relatively recently the prevailing concept in antiarrhythmic therapy was that arrhythmias could be controlled by drugs which slowed conduction or suppressed automaticity, goals well served by the sodium channel-blocking drugs and glycosides. Drug re search was based largely on the development of agents mimicking those already available, but with greater efficacy, fewer side effects or a more favourable phar macokinetic profile. The CAST trial stands out as a landmark in the evolution of arrhytmia manage ment; rarely has a single trial had such a profound impact not only on clinical prac tice, but also on the whole approach of those involved in the research, development and regulation of antiarrhythmic drugs. The results of the CAST trial, designed to redress the shortcomings of earlier trials which had failed to demonstrate the anticipated improvement in mortality post-myocardial infarction with the use of class I agents, are well known. The CAST and CAST II showed an increase in mor tality associated with the active agent (encainide, flecainide or morizicine) com pared to placebo treatment. They firmly established the potential danger in the use of class I drugs.

Mechanisms of Antiarrhythmic and Proarrhythmic Actions

Antiarrhythmic Drugs

A. John Camm

Atrial Fibrillation is becoming a twenty-first century epidemic. It remains the most common form of sustained arrhythmia with significant mortality, morbidity and cost to the health care system. It is the most common cause of hospital admissions among all arrhythmias. Its prevalence increases with the aging population and is often associated with many other cardiac and noncardiac conditions, most notably congestive heart failure, hypertension, diabetes, and coronary artery disease. Although significant progress in understanding the epidemiology, natural history and mechanism has been made, the antiarrhythmic therapy in patients with Atrial Fibrillation is less satisfactory. Management of Atrial Fibrillation: A Practical Approach is the perfect pocket guide for those who care for patients afflicted by Atrial Fibrillation. From the history of the condition and the subsets of patients, to therapeutic and preventive procedures, Management of Atrial Fibrillation comprehensively covers all aspects in managing this increasingly prevalent disorder. Written by leading authorities in the field with vast experience in practical medicine, the book creates a clinically orientated, evidence based "fast fact" type resource for cardiologists, trainees and related healthcare professionals.

Mohammad Shenasa

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