Nikolaos Limnios

Mounir Mesbah

Mikhail S. Nikulin

Catherine Huber

Reliability and survival analysis are important applications of stochastic mathematics (probability, statistics and stochastic processes) that are usually covered separately in spite of the similarity of the involved mathematical theory. This title aims to redress this situation: it includes 21 chapters divided into four parts: Survival analysis, Reliability, Quality of life, and Related topics. Many of these chapters were presented at the European Seminar on Mathematical Methods for Survival Analysis, Reliability and Quality of Life in 2006.

Mathematical Methods in Survival Analysis, Reliability and Quality of Life

Karl Bang Christensen

Svend Kreiner

The family of statistical models known as Rasch models started with a simple model for responses to questions in educational tests presented together with a number of related models that the Danish mathematician Georg Rasch referred to as models for measurement. Since the beginning of the 1950s the use of Rasch models has grown and has spread from education to the measurement of health status. This book contains a comprehensive overview of the statistical theory of Rasch models. Part 1 contains the probabilistic definition of Rasch models, Part 2 describes the estimation of item and person parameters, Part 3 concerns the assessment of the data-model fit of Rasch models, Part 4 contains applications of Rasch models, Part 5 discusses how to develop health-related instruments for Rasch models, and Part 6 describes how to perform Rasch analysis and document results.

Rasch Models in Health

Bernard F. Cole

Mei-Ling Ting Lee

On October 16 and 17, 2000, we hosted an international workshop entitled "Statistical Design, Measurement, and Analysis of Health Related Quality of Life." The workshop was held in the beautiful city of Arradon, South Brittany, France with the main goal of fostering an interdisciplinary forum for discussion of theoretical and applied statistical issues arising in studies of health-related quality of life (HRQoL). Included were biostatisticians, psychometricians and public health professionals (e.g., physicians, sociologists, psychologists) active in the study ofHRQoL. In assembling this volume, we invited each conference participant to contribute a paper based on his or her presentation and the ensuing and very interesting discussions that took place in Arradon. All papers were peer-reviewed, by anonymous reviewers, and revised before final editing and acceptance. Although this process was quite time consuming, we believe that it greatly improved the volume as a whole, making this book a valuable contribution to the field ofHRQoL research. The volume presents a broad spectrum of papers presented at the Workshop, and thus illustrates the range of current research related to the theory, methods and applications of HRQoL, as well as the interdisciplinary nature ofthis work. Following an introduction written by Sir David Cox, it includes 27 articles organized into the following chapters.

Design, Measurements and Analysis

Statistical Methods for Quality of Life Studies

Mounir Mesbah

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