Dinesh Chandra Verma

Jon Crowcroft

Pietro Liò

Eiko Yoneki

This volume contains the papers from BIOWIRE 2007, the first in a series of wo- shops on the bio-inspired design of networks, and additional papers contributed from the research area of bio-inspired computing and communication. The workshop took place at the University of Cambridge during April 2–5, 2007 with sponsorship from the US/UK International Technology Alliance in Network and Information Sciences. Its objective was to present, discuss and explore the recent developments in the field of bio-inspired design of networks, with particular regard to wireless networks and the self-organizing properties of biological networks. The workshop was organized by Jon Crowcroft (University of Cambridge), Don Towsley (University of Massachusetts), Dinesh Verma (IBM T. J. Watson Research Center), Vasilis Pappas (IBM T. J. Watson Research Center), Ananthram Swami (ARL), Tom McCutcheon (DSTL) and Pietro Liò (University of Cambridge). The program for BIOWIRE 2007 included 54 speakers covering a diverse range of topics, categorized as follows: 1. Self-organized communication networks in insects 2. Neuronal communications 3. Bio-computing 4. Epidemiology 5. Network theory 6. Wireless and sensorial networks 7. Brain: models of sensorial integration The BIOWIRE workshop focuses on achieving a common ground for knowledge sharing among scientists with expertise in investigating the application domain (e. g. , biological, wireless, data communication and transportation networks) and scientists with relevant expertise in the methodology domain (e. g. , mathematics and statistical physics of networks).

First Workshop on Bio-Inspired Design of Networks, BIOWIRE 2007 Cambridge, UK, April 2-5, 2007, Revised Papers

Bio-Inspired Computing and Communication

Paolo Zuliani

This book presents outstanding contributions in an exciting, new and multidisciplinary research area: the application of formal, automated reasoning techniques to analyse complex models in systems biology and systems medicine. Automated reasoning is a field of computer science devoted to the development of algorithms that yield trustworthy answers, providing a basis of sound logical reasoning. For example, in the semiconductor industry formal verification is instrumental to ensuring that chip designs are free of defects (or “bugs”). Over the past 15 years, systems biology and systems medicine have been introduced in an attempt to understand the enormous complexity of life from a computational point of view. This has generated a wealth of new knowledge in the form of computational models, whose staggering complexity makes manual analysis methods infeasible. Sound, trusted, and automated means of analysing the models are thus required in order to be able to trust their conclusions. Above all, this is crucial to engineering safe biomedical devices and to reducing our reliance on wet-lab experiments and clinical trials, which will in turn produce lower economic and societal costs. Some examples of the questions addressed here include: Can we automatically adjust medications for patients with multiple chronic conditions? Can we verify that an artificial pancreas system delivers insulin in a way that ensures Type 1 diabetic patients never suffer from hyperglycaemia or hypoglycaemia? And lastly, can we predict what kind of mutations a cancer cell is likely to undergo? This book brings together leading researchers from a number of highly interdisciplinary areas, including: · Parameter inference from time series · Model selection · Network structure identification · Machine learning · Systems medicine · Hypothesis generation from experimental data · Systems biology, systems medicine, and digital pathology · Verification of biomedical devices “This book presents a comprehensive spectrum of model-focused analysis techniques for biological systems ...an essential resource for tracking the developments of a fast moving field that promises to revolutionize biology and medicine by the automated analysis of models and data.”Prof Luca Cardelli FRS, University of Oxford

Automated Reasoning for Systems Biology and Medicine

Roberto Tagliaferri

Clelia DI Serio

Alessandro Nonis

This book constitutes the thoroughly refereed post-conference proceedings of the 11th International Meeting on Computational Intelligence Methods for Bioinformatics and Biostatistics, CIBB 2014, held in Cambridge, UK, in June 2014. The 25 revised full papers presented were carefully reviewed and selected from 44 submissions. The papers focus problems concerning computational techniques in bioinformatics, systems biology, medical informatics and biostatistics.

11th International Meeting, CIBB 2014, Cambridge, UK, June 26-28, 2014, Revised Selected Papers

Computational Intelligence Methods for Bioinformatics and Biostatistics

Pietro Liò

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