WIRED

Rachael Pells

Genome sequencing is one of the most exciting scientific breakthroughs of the past thirty years. But what precisely does it involve and how is it developing? In this brilliantly wide-ranging, one-stop guide WIRED journalist Rachael Pells explains the science behind genomics. She analyses its practical applications in medical diagnosis and the treatment of conditions that range from cancer to severe allergic reactions to cystic fibrosis. She considers its potential to help with advances in agriculture and environmental science. She explores the ethics of genetic modification and the dangers involved when humans 'play God'. And she addresses the fundamental question: to what extent will future advances transform human longevity and the quality of life.

How Genome Sequencing Will Change Our Lives

Genomics (WIRED guides)

Robert-Jan H. M. Smits

This is the story of open access publishing - why it matters now, and for the future. In a world where information has never been so accessible, and answers are available at the touch of a fingertip, we are hungrier for the facts than ever before - something the Covid-19 crisis has brought to light. And yet, paywalls put in place by multi-billion dollar publishing houses are still preventing millions from accessing quality, scientific knowledge - and public trust in science is under threat. On 4 September 2018, a bold new initiative known as 'Plan S' was unveiled, kickstarting a world-wide shift in attitudes towards open access research. For the first time, funding agencies across continents joined forces to impose new rules on the publication of research, with the aim of one day making all research free and available to all. What followed was a debate of global proportions, as stakeholders asked: Who has the right to access publicly-funded research? Will it ever be possible to enforce change on a multi-billion dollar market dominated by five major players? Here, the scheme's founder, Robert-Jan Smits, makes a compelling case for Open Access, and reveals for the first time how he set about turning his controversial plan into reality - as well as some of the challenges faced along the way. In telling his story, Smits argues that the Covid-19 crisis has exposed the traditional academic publishing system as unsustainable.--

Rachael Pells

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