Ricard Cervera

Munther A. A. Khamashta

Graham R. V. Hughes

Since the original description of antibodies to endothelial cells in the early 1970s, and with the advent of sensitive and reproducible techniques for their detection, the scope for investigating the vascular damage of immunological disorders has widened considerably. In this book, leading world scientists have contributed chapters presenting broad coverage of basic science and clinical implications of immunological interactions of antibodies to endothelial cells. The book takes a multidisciplinary approach that will appeal to immunologists, rheumatologists, internists, and others interested in the subject.

Antibodies to Endothelial Cells and Vascular Damage

M. Eric Gershwin

Yehuda Shoenfeld

According to the Autoimmune Diseases Coordinating Committee (ADCC), between 14.7 and 23.5 million people in the USA – up to eight percent of the population are affected by autoimmune disease. Autoimmune diseases are a family of more than 100 chronic, and often disabling, illnesses that develop when underlying defects in the immune system lead the body to attack its own organs, tissues, and cells. In Handbook of Autoimmune Disease, the editors have gathered in a comprehensive handbook a critical review, by renowned experts, of more than 100 autoimmune diseases, divided into two main groups, namely systemic and organ-specific autoimmune diseases. A contemporary overview of these conditions with special emphasis on diagnosis is presented. Each chapter contains the essential information required by attending physicians as well as bench scientists to understand the definition of a specific autoimmune disease, the diagnostic criteria, and the treatment.

Diagnostic Criteria in Autoimmune Diseases

Antonio Serrano

Jean-Christophe Raymond Gris

Primary Antiphospholipid Syndrome

Ricard Cervera

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