Ryuichi Matsuno

Shuichi Yamamoto

Kazahiro Nakanishi

Showing chemists how to predict ion-exchange chromatography (IEC) separation behaviour and how to determime appropriate operating conditions, this reference illustrates procedures, apparatus and types of ion exchanges, emphasizing the design and application of large-scale IEC. Complete with more than 100 useful tables and diagrams, this text explains the effects of each variable on separation behaviour; compares models and equations describing behaviour of proteins in IEC with experimental results; introduces design calculation procedures for scale up, adapting IEC for individual requirements; discusses parameters affecting separation behaviour, including adsorption equilibria, stationary phase diffusion and axial dispersion; provides examples of applications, such as high or medium performance IEC and large scale operations and reviews both theorectical and experimental literature. This text serves as an reference for analytical, agricultural, food, and pharmaceutical chemists, chromatographers, food scientists and technologists, biochemists and biotechnologists.

Ion-Exchange Chromatography of Proteins

Shintaro Furusaki

Isao Endo

Biochemical engineering forms a bridge between fundamental biochemical research and large scale biotechnology processes. It covers genetic and protein engineering, cell culture, bioprocess and reactor design, separation and modelling. Research work in biochemical engineering is an investment in the future, when conventional resources will have to be replaced with renewable ones. In this book the papers presented at the Asia-Pacific Biochemical Engineering Conference (Yokohama, Japan 1992) are collected. This collection is unique in its wide coverage of topics and it gives an overview of the current trends of research in an important area.

Ryuichi Matsuno

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