Takashi Suzuki

This authoritative monograph presents in detail classical and modern methods for the study of semilinear elliptic equations, that is, methods to study the qualitative properties of solutions using variational techniques, the maximum principle, blowup analysis, spectral theory, topological methods, etc. The book is self-contained and is addressed to experienced and beginning researchers alike.

Classical and Modern Theories

Semilinear Elliptic Equations

The purpose of this monograph is to describe recent developments in mathematical modeling and mathematical analysis of certain problems arising from cell biology. Cancer cells and their growth via several stages are of particular interest. To describe these events, multi-scale models are applied, involving continuously distributed environment variables and several components related to particles. Hybrid simulations are also carried out, using discretization of environment variables and the Monte Carlo method for the principal particle variables. Rigorous mathematical foundations are the bases of these tools.The monograph is composed of four chapters. The first three chapters are concerned with modeling, while the last one is devoted to mathematical analysis. The first chapter deals with molecular dynamics occurring at the early stage of cancer invasion. A pathway network model based on a biological scenario is constructed, and then its mathematical structures are determined. In the second chapter mathematical modeling is introduced, overviewing several biological insights, using partial differential equations. Transport and gradient are the main factors, and several models are introduced including the Keller‒Segel systems. The third chapter treats the method of averaging to model the movement of particles, based on mean field theories, employing deterministic and stochastic approaches. Then appropriate parameters for stochastic simulations are examined. The segment model is finally proposed as an application. In the fourth chapter, thermodynamic features of these models and how these structures are applied in mathematical analysis are examined, that is, negative chemotaxis, parabolic systems with non-local term accounting for chemical reactions, mass-conservative reaction-diffusion systems, and competitive systems of chemotaxis. The monograph concludes with the method of the weak scaling limit applied to the Smoluchowski‒Poisson equation.

Mathematical Methods for Cancer Evolution

A unique feature of the book compared to classical monographs on GE is its emphasis on the historical nature of the subject, and not only the mathematical nature. Students are expected to learn that those mathematically formidable techniques are indeed necessary for tackling many economic problems which have been significant not only in the mathematical or technical context, but also in the historical and traditional context.

General Equilibrium Analysis of Production and Increasing Returns

The aim of this book is to incorporate Marshallian ideas such as external increasing returns and monopolistic competitions into the general equilibrium framework of Walrasian tradition. New chapters and sections have been added to this revised and expanded edition of General Equilibrium Analysis of Production and Increasing Returns (World Scientific, 2009).The new material includes a presentation of equilibrium existence and core equivalence theorems for an infinite horizon economy with a measure space of consumers. These results are currently the focus of extensive studies by mathematical theorists, and are obtained by an application of an advanced mathematical concept called saturated (super-atomless) measure space.The second major change is the inclusion of a simple toy model of a liberal society which implements the difference principle proposed by J Rawls as a principle of distributive justice. This new section opens up a possibility to connect theoretical economics and political philosophy.Thirdly, the author presents the marginal cost pricing equilibrium and discusses welfare properties of the external increasing returns, which also belong to Marshall/ Pigou tradition of the Cambridge school.Finally, a new mathematical appendix treats basics of singular homology theory. Although the fixed point theorem is originally a theorem of algebraic topology, most economic students know its proof only in the context of the differentiable manifold theory presented by J Milnor. Considering the significance of the fixed point theorem and its playing a key role in general equilibrium theory, the purpose of this new appendix is to provide readers with the idea of a proof of Brower's fixed point theorem from the 'right place'.This volume will be helpful for graduate students and researchers of mathematical economics, game theory, and microeconomics.

Fundamentals Of General Equilibrium Analysis

Clair Poignard

Mark Chaplain

Vito Quaranta

This book presents original papers reflecting topics featured at the international symposium entitled “Fusion of Mathematics and Biology” and organized by the editor of the book. The symposium, held in October 2020 at Osaka University in Japan, was the core event for the final year of the research project entitled “Establishing International Research Networks of Mathematical Oncology.” The project had been carried out since April 2015 as part of the Core-to-Core Program of Japan Society for the Promotion of Science (JSPS). In this book, the editor presents collaborative research from prestigious organizations in France, the UK, and the USA. By utilizing their individual strengths and realizing the fusion of life science and mathematical science, the project achieved a combination of mathematical analysis, verification by biomedical experiments, and statistical analysis of chemical databases. Mathematics is sometimes regarded as a universal language. It is a valuable property that everyone can understand beyond the boundaries of culture, religion, and language. This unifying force of mathematics also applies to the various fields of science. Mathematical oncology has two aspects, i.e., data science and mathematical modeling, and definitely helps in the prediction and control of biological phenomena observed in cancer evolution. The topics addressed in this book represent several methods of applying mathematical modeling to scientific problems in the natural sciences. Furthermore, novel reviews are included that may motivate many mathematicians to become interested in biological research.

Fusion of Mathematics and Biology, Osaka, Japan, October 26–28, 2020

Methods of Mathematical Oncology

* Examines a nonlinear system of parabolic PDEs arising in mathematical biology and statistical mechanics * Describes the whole picture, i.e., the mathematical and physical principles * Suitable for researchers and grad students in mathematics and applied mathematics who are interested in nonlinear PDEs in stochastic processes, cellular automatons, variational methods, and their applications to physics, chemistry, biology, and engineering

Free Energy and Self-Interacting Particles

Shunʼichi Noguchi

Toshiyuki Takamiya

Tsuyoshi Mukai

Essays on Arthurian themes, on Beowulf, Chaucer and Shakespeare, and textual studies of Gower and others.

Takashi Suzuki

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