Eric Hollander

Trevor W. Robbins

David Belin

Margarita Moreno

This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Impulsive Compulsive Spectrum Disorders

David J. Nutt

Barry J. Everitt

In the past two decades, there have been astonishing advances in our understanding of the neurobiological basis and nature of drug addiction. We now know the initial molecular sites of action, at identified receptors, of virtually all of the major drugs of abuse including cocaine, heroin, and amphetamine, as well as legal drugs such as nicotine and alcohol. We also understand the main components of a 'reward system' and its connections to major brain regions involved in motivation and emotion, such as the amygdala, hippocampus, and prefrontal cortex. The Neurobiology of Addiction describes the latest advances in our understanding of addiction. It brings together world class researchers to debate the nature and extent of addiction, as well as its causes, consequences, and treatment. The focus of the book is on the brain processes underlying addiction, in terms of neural systems, neurochemical basis, and molecular changes. Several types of addiction are discussed ranging from illicit drugs - cocaine, amphetamine, and heroin to legal drugs - alcohol and nicotine. In addition, it explores increasingly common behavioural addictions such as gambling and obesity. Included are chapters on vulnerability to addiction, genetic factors, opponent motivational processes, animal models, relapse, cognitive deficits associated with drug abuse, new pharmacological treatments, and current controversies concerning different neuropsychological theories of addiction. Throughout, it reports on cutting edge research using brain imaging, and state of the art molecular methodology. The book will make fascinating reading for students and teachers in the field of neuroscience, pharmacology and psychology, as well as experts in the field.

New Vistas

The Neurobiology of Addiction

Naomi A. Fineberg

The book highlights important new research approaches of clinical relevance, written by prominent researchers in the field of OCD and related disorders. A broad range of topics is covered, beginning with a description of the phenotypic features of the OCD followed by chapters on developmental aspects, animal models, genetic and biological models including neuro-inflammation, functional neuroimaging correlates and information-processing accounts. Finally, existing and novel treatment approaches are covered including clinical and pharmacogenetic treatment models. In this way the volume brings together the key disciplines involved in the neurobiological understanding of OCD to provide an update of the field and outlook to the future. Together, the volume chapters provide focused and critical reviews that span a broad range of topics suitable for both students and established investigators and clinicians interested in the present state of OCD research.

The Neurobiology and Treatment of OCD: Accelerating Progress

Maria A. Ron

This authoritative new book details the most recent advances in clinical neuroscience, from neurogenetics to the study of consciousness.

Disorders of Brain and Mind: Volume 2

Andrew Jackson

Gerald V. Stimson

Martin Ince

Drugs and the Future presents 13 reviews collected to present the new advances in all areas of addiction research, including knowledge gained from mapping the human genome, the improved understanding of brain pathways and functions that are stimulated by addictive drugs, experimental and clinical psychology approaches to addiction and treatment, as well as both ethical considerations and social policy. The book also includes chapters on the history of addictive substances and some personal narratives of addiction. Introduced by Sir David King, Science Advisory to the UK Government and head of the Office of Science and Technology, and Nora Volkow, director of the National Institute on Drug Abuse in the USA, the book uniquely covers the full range of disciplines which can provide insight into the future of addiction, from genetics to the humanities. Written for a scientific audience, it is also applicable to non-specialists as well. Provides an unique overview of what we know about addiction, and how scientific knowledge can and should be applied in the societal, ethical, and political context Applies the state-of-the-art research in fields such as Genomics, Neuroscience, Pharmacology, Social Policy and Ethics to addiction research Includes a preface by Sir David King, Science Advisory to the UK Government and head of the Office of Science and Technology, and in introduction by Nora Volkow, director of the National Institute on Drug Abuse in the USA

Brain Science, Addiction and Society

Drugs and the Future

Mauricio R. Delgado

Elizabeth A. Phelps

Papers originally presented at a workshop conference convened in Stowe, Vermont on July 13-17 2008, as part of the Attention and Peformance series.

Attention and Performance XXIII

Decision Making, Affect, and Learning

This latest volume in the critically acclaimed and highly influential Attention and Performance series focuses on two of the fastest moving research areas in cognitive and affective neuroscience - decision making and emotional processing. Decision Making, Affect, and Learning investigates the psychological and neural systems underlying decision making, and the relationship with reward, affect, and learning. In addition, it considers neurodevelopmental and clinical aspects of these issues - for example the role of decision making and reward in drug addiction. It also looks at the applied aspects of this knowledge to other disciplines, including the growing field of Neuroeconomics. After an introductory chapter from the Volume editors, the book is then arranged according to the following themes: Psychological Processes underlying decision-making. Neural systems of decision-making Neural systems of emotion, reward and learning Neurodevelopmental and clinical aspects Superbly written and edited, the book highlights the complex interplay between emotional and decision-making processes and their relationship with learning.

Trevor W. Robbins

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