Yadin Dudai

Department of Neurobiology Yadin Dudai

This is the first book on the neurobiology of learning and memory that covers comprehensively all levels of analysis, from molecules to brain, in both invertebrates and vertebrates, from molluscs to man. The book addresses in a provocative, stimulating, and lucid manner the major questions, concepts, and experimental approaches in the biology of learning and memory, and describes, analyses, and integrates recent findings and hypotheses. The result is a fascinating, clear, and balanced picture of the state of the art at one of the frontiers of brain research.

Concepts, Findings, Trends

The Neurobiology of Memory

Henry L. Roediger III

Susan M. Fitzpatrick

Scientists currently study memory from many different perspectives: neurobiological, ethological, animal conditioning, cognitive, behavioral neuroscience, social, and cultural. The aim of this book is to help initiate a new science of memory by bringing these perspectives together to create a unified understanding of the topic. The book began with a conference where leading practitioners from all these major approaches met to analyze and discuss 16 concepts that are crucial to our understanding of memory. Each of these 16 concepts is addressed in a section of the book, and in the 66 succinct chapters that fill these sections, a leading researcher addresses the section's concept by clearly stating his or her position on it, elucidating how it is used, and discussing how it should be used in future research. For some concepts, there is general agreement among practitioners from different fields and levels of analysis, but for others there is general disagreement and much controversy. A final chapter in each section, also written by a leading researcher, integrates the various viewpoints offered on the section's concept, then draws conclusions about the concept. This groundbreaking volume will be an indispensable reference for all the students and researchers who will build upon the foundation it provides for the new science of memory.

Concepts

Science of Memory

Science of Memory Concepts

Eric R. Kandel

Mark R. Mayford, Ph.d.

We learn and remember information by modifying synaptic connections in the neuronal networks of our brain. Depending on the type of information being stored, these changes occur in different regions and different circuits of the brain. The underlying circuit mechanisms are beginning to be understood. These mechanisms are capable of storing or reconstructing memories for periods ranging up to a lifetime, but they are also error-prone, as memories can be distorted or lost. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Biology examines important aspects of the neurobiology of learning and memory. Contributors review the various types of memory and the anatomical architectures and specialized cells involved. The induction of synaptic and cell-wide changes during memory encoding, the transcriptional and translational programs required for memory stabilization, the molecular signals that actively maintain memories, and the activation of neural ensembles during memory retrieval are comprehensively covered. The authors also discuss the model organisms and state-of-the-art technologies used to elucidate these processes. This volume will serve as a valuable reference for all neurobiologists and biomedical scientists as well as for cognitive and computational neuroscientists wishing to explore the remarkable phenomena of learning and memory.

Learning and Memory

Alcino J. Silva

The convergence of neuroscience, philosophy, art, music, and literature offers valuable new insights into the study of memory. The Memory Process offers a groundbreaking, interdisciplinary approach to the understanding of human memory, with contributions from both neuroscientists and humanists. The first book to link the neuroscientific study of memory to the investigation of memory in the humanities, it connects the latest findings in memory research with insights from philosophy, literature, theater, art, music, and film. Chapters from the scientific perspective discuss both fundamental concepts and ongoing debates from genetic and epigenetic approaches, functional neuroimaging, connectionist modeling, dream analysis, and neurocognitive studies. The humanist analyses offer insights about memory from outside the laboratory: a taxonomy of memory gleaned from modernist authors including Virginia Woolf, James Joyce, and William Faulkner; the organization of memory, seen in drama ranging from Hamlet to The Glass Menagerie; procedural memory and emotional memory in responses to visual art; music's dependence on the listener's recall; and the vivid renderings of memory and forgetting in such films as Memento and Eternal Sunshine of the Spotless Mind. The chapters from the philosophical perspective serve as the bridge between science and the arts. The volume's sweeping introduction offers an integrative merging of neuroscientific and humanistic findings. Contributors John Bickle, Jean-Pierre Changeux, Valérie Doyère, Yadin Dudai, Atillio Favorini, John Burt Foster, David Freedberg, Walter Glannon, Robert Stickgold, David Hertz, William Hirstein, Joseph LeDoux, Paul Matthews, James L. McClelland, Suzanne Nalbantian, Isabelle Peretz, Alan Richardson, Edmund Rolls, Séverine Samson, Alcino Silva, Barbara Tillmann, Fernando Vidal

Yadin Dudai

Books

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