Yogesh Dwivedi

Ashok Kumar

Brandi K Ormerod

Jakob W Streit

Aging is one of the major risk factors for the onset and progression of various neurodegenerative diseases. Neuroinflammation is a common feature of virtually every central nervous system disease, and is acknowledged as a likely mediator of cognitive impairments. Systemic inflammation levels are augmented with advanced age and neurodegeneration. The influence of age on neuroinflammatory responses including glial activation, increased production of proinflammatory cytokines, and aberrant neuronal signaling could magnify the deterioration of the central nervous system microenvironment in disease, and may contribute to enhanced cognitive impairment. This eBook is a collection of highly informative original research articles, providing comprehensive aspect of neuroinflammation and possible therapeutic interventions in rescuing cognitive impairments.

Neuroinflammation and Cognition

With recent studies using genetic, epigenetic, and other molecular and neurochemical approaches, a new era has begun in understanding pathophysiology of suicide. Emerging evidence suggests that neurobiological factors are not only critical in providing potential risk factors but also provide a promising approach to develop more effective treatment

The Neurobiological Basis of Suicide

Emmanuel Ayaburi

Richard Boateng

John Effah

This book constitutes the refereed proceedings of the IFIP WG 8.6 International Working Conference "ICT Unbounded, Social Impact of Bright ICT Adoption" on Transfer and Diffusion of IT, TDIT 2019, held in Accra, Ghana, in June 2019. The 30 revised full papers and 4 short papers presented were carefully reviewed and selected from 72 submissions. The papers focus on Bright Information and Communication Technology, a concept that entails the development of relevant technologies, business models, public policies, social norms, international agreements, metrics of measuring national progress and preventing undesirable activities on the Internet. They are organized in the following topical sections: technology adoption, diffusion and ubiquitous computing; big data and business intellligence; smart cities; and security, privacy, ethics and misinformation.

IFIP WG 8.6 International Conference on Transfer and Diffusion of IT, TDIT 2019, Accra, Ghana, June 21–22, 2019, Proceedings

ICT Unbounded, Social Impact of Bright ICT Adoption

With recent studies using genetic, epigenetic, and other molecular and neurochemical approaches, a new era has begun in understanding pathophysiology of suicide. Emerging evidence suggests that neurobiological factors are not only critical in providing potential risk factors but also provide a promising approach to develop more effective treatment and prevention strategies. The Neurobiological Basis of Suicide discusses the most recent findings in suicide neurobiology. Psychological, psychosocial, and cultural factors are important in determining the risk factors for suicide; however, they offer weak prediction and can be of little clinical use. Interestingly, cognitive characteristics are different among depressed suicidal and depressed nonsuicidal subjects, and could be involved in the development of suicidal behavior. The characterization of the neurobiological basis of suicide is in delineating the risk factors associated with suicide. The Neurobiological Basis of Suicide focuses on how and why these neurobiological factors are crucial in the pathogenic mechanisms of suicidal behavior and how these findings can be transformed into potential therapeutic applications.

Yogesh Dwivedi

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