In 1960, Memphis debutante Margaret McLain defies conservative Southern society by entering veterinary school. Soon young Dr. Maggie McLain finds herself battling for respect among the farmers, pet owners, and livestock breeders of western Tennessee, while also juggling marriage, kids, and a bevy of loving but rambunctious friends -- both two-footed and four-footed. As the decades pass, Maggie's courage and dedication become legendary. Yet when tragedy strikes her family, Maggie has to make a poignant decision about her future in the profession she adores.