Wastewater pollution is a major issue in the context of the future circular economy because all matter should be ultimately reused, calling for efficient depollution techniques. This book present timely reviews on the treatment of wastewater contaminated by organic pollutants, with focus on aerobic granulation and degradation. Organic pollutants include microplastics, phthalates, humic acids, polycyclic aromatic hydrocarbons, pharmaceutical drugs and metabolites, plastics, oil spills, petroleum hydrocarbons, personal care products, tannery waste, dyes and pigments.