This book constitutes the refereed proceedings of the 2nd International Joint Conference of the 10th Ibero-American Conference on Artificial Intelligence, IBERAMIA 2006, and the 18th Brazilian Artificial Intelligence Symposium, SBIA 2006. The book presents 62 revised full papers together with 4 invited lectures. Topical sections include AI in education and intelligent tutoring systems, autonomous agents and multiagent systems, computer vision and pattern recognition, evolutionary computation and artificial life, and more.