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Amphetamine-type stimulants (ATS) use can result in long-term health and social welfare problems for the user, as well as criminal justice concerns and lost productivity costs for the wider community. In any population of young people, whether among the mainstream of society or not, there is a large portion of individuals that are not using ATS, or are using them experimentally, and who would benefit from measures and messages that encourage non-use. The present guide considers policy options designed to develop effective preventive efforts on these young people.