Joint FAO/WHO Expert Committee on Food Additives. Meeting

This document contains monographs on residue evaluations of certain veterinary drugs, prepared at the seventy-eight meeting of the Joint FAO/WHO Expert Committee on Food Additives (JECFA), which was held in Geneva, Switzerland, from 5 to 14 November 2013. Four substances were evaluated for the first time--emamectin benzoate, gentian violet, lasalocid sodium and zilpaterol hydrochloride. Four additional substances were re-evaluated--derquantel, ivermectin, monepantel and recombinant bovine somatotrophins. The monographs provide information on chemical identity and properties of the compounds, pharmacokinetics and metabolism, residue depletion studies and analytical methods validated and used for the detection and quantification of the compounds. In addition, this document provides an overview of the pilot project to evaluate alternative approaches to estimate daily intakes of residues of veterinary drugs in foods and provides guidance on the extrapolation of MRLs to minor species and for the establishment of MRLs in honey. This publication and other documents produced by JECFA contain information that is useful to all those who work with or are involved with recommending or controlling maximum residue limits for veterinary drugs in foods of animal origin.

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