Learn-Han Lee

Pendru Raghunath

Vibrio are Gram-negative bacteria that naturally inhabit riverine, estuarine and marine aquatic environments. Some Vibrio are known to be capable of causing gastroenteritis, wound infections, cholera and fatal septicemia in severe cases. Over the past decades, research on Vibrio has increased and has caused a great development in our knowledge of these pathogens. Focus of this research includes the discovery of emerging epidemic clones, the traits of new strains, and the occurrence of multidrug resistant strains in the ecology. Moreover, improved understandings of the prevalence, pathogenesis and evolution of Vibrio have revealed the significant role of these pathogens in enhancing disease transmission. The complete genomic sequences of Vibrio have been determined in providing a rich set of data illuminating the metabolic versatility of the species. This book is dedicated to improving our knowledge and understanding, not solely focusing into the prevalence, detection, pathogenesis, virulence, pandemic clones and multidrug resistance, but also looking at the management of the multidrug resistance through different strategies such as non-antibiotic resistant strategies that involved the application of knowledge in bacteriophages.

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