Canada. Health and Welfare Canada

Martin T. Schechter

Canadian AIDS Society

This document reviews alternative designs in clinical trials of HIV therapies, particularly the concept of open arms, and discusses the relative advantages and disadvantages of such designs. Material is based on submissions and letters to the Expert Advisory Committee on HIV Therapies or to the Department of Health and Welfare, background papers distributed to the Committee, and extensive discussion. The document presents an overview of the various opinions expressed and offers a variety of opinions.

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