William Montagna

Richard L. Dobson

Advances in Biology of Skin, Volume VII: Carcinogenesis covers proceedings of the 15th Symposium on the Biology of Skin, held at the Oregon Regional Primate Research Center on April 9-11, 1965, under the auspices of the University of Oregon Medical School. This book is composed of nineteen chapters, and begins with the mechanism of tissue homeostasis in adult mammals and the kinetics of epidermal reaction to carcinogenic agents and other skin irritants. The succeeding chapters deal with the growth promoting effects of tumors on tissues, the reaction pattern distinctions between normal and neoplastic epithelium, and some biological implications of chemical carcinogenesis. Considerable chapters are devoted to various carcinogens, including hydrocarbons, viruses, androgens, and estrogens. Other chapters consider the physicochemical mechanisms of acceleration of skin carcinogenesis and experimental observations of environmental carcinogenesis. The mechanisms of skin cancer induction due to ultraviolet radiation, as well as arsenic induced tumors are examined. The concluding chapters describe some forms of skin tumors, such as adnexal tumors and basal cell epithelioma. This book will prove useful to oncologists and researchers in the field of carcinogenesis.

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