Peng Hu

Xiaoyue Zhou

Rob J. Van Der Geest

Yucheng Chen

 Ming Yen Ng

In the past decades, advanced quantitative indexes obtained by cardiovascular magnetic resonance imaging (CMRI), such as myocardial strain, myocardial T1/ECV/T2/T2* relaxation value, myocardial blood flow quantification index and hemodynamics indexes, have been proposed as an alternative for non-invasive quantitative evaluation in various cardiovascular diseases. Those quantitative indexes have been proven to be more sensitive in assessing the early change of myocardial tissue, ventricular function, or hemodynamics, compared to the conventional qualitative methods. However, there are many challenges in the accurate measurement of those indexes as well as the evaluation of their clinical significance in the diagnosis and prognosis of a certain disease. Besides, quality control and standardization of those indexes become crucial when promoting them into clinical practice. This Research Topic will offer comprehensive reviews and original research articles of the newly emerged quantitative CMRI methods and the clinical insights of the diagnostic and prognostic value of those advanced CMRI indexes. CMRI techniques such as myocardial strain analysis, quantitative myocardial tissue mapping, 2-dimensional / 4-dimensional flow quantification and quantitative perfusion will be of our interest. The aim of this Research Topic will be to highlight the promising technical improvements in the accurate measurement of the CMRI indexes, and/or the added value of those indexes in disease diagnosis and prognosis. Meanwhile, quality control and standardization of the advanced CMRI indexes in multi-centre / multi-vendor research projects will be discussed.

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